Hikma warns sales will be lower after delay to asthma drug launch
Drug maker Hikma has cut its full-year revenue forecasts after its plan to launch a cheap copy of a top-selling asthma drug this year hit a major roadblock.
The FTSE 100 company was forced to lower estimates for its generics unit by $130m on Friday - bringing overall revenue forecasts down as much as 9pc - after a US regulator blocked its application to launch a copycat version of GlaxoSmithKline's asthma drug Advair.
Hikma's shares dropped more than 5pc on Friday, while shares in Glaxo - which is likely to see sales of the drug tumble if rivals launch cheaper versions - inched up.....
Read more here: telegraph.co.uk
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Could This Cancer Drug Benefit Patients with Severe Asthma?
An early-phase study suggests that a targeted cancer drug, imatinib (Gleevec, Novartis), may help treat patients with severe asthma.1 Although the small-scale study was not large enough to confirm its results, the researchers found that measures of airway inflammation were reduced in participants taking the drug.
The results, which were published in The New England Journal of Medicine, showed that the chronic myeloid leukemia drug targets specific immune cells that are known to cause lung inflammation. The study was conducted in part at Washington University School of Medicine in St. Louis and led by Brigham and Women’s Hospital and Harvard Medical School.....
Read more here: pharmacytimes.com
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Handbook on asthma a good place to start
The Asthma Association of Barbados recently launched a book designed to aid asthmatics in the better management of their condition. A glance through that handbook will show that the Association tried its best to cover the full gamut of topics that often surface when discussions come up about asthma.
The Asthma Handbook, entitled “Asthma Treatment and Control: Volume 1”, defines what asthma is, its causes, its symptoms, the risk factors for developing the condition, triggers of asthma, treatment of asthma, the correct use of the asthma inhaler, the spacing device and other apparatus. It also contains an Asthma Action Plan and a section on managing asthma in the home, in schools and the work environment.....
Read more here: barbadosadvocate.com
Saturday, May 20, 2017
Friday, May 19, 2017
Cancer drug may help patients with severe asthma
Therapy targets immune cells driving lung inflammation
A small clinical trial suggests that some patients with severe asthma may benefit from treatment with a targeted cancer drug. The study, conducted in part at Washington University School of Medicine in St. Louis, showed that imatinib (brand name Gleevec), commonly prescribed to treat chronic myeloid leukemia, also targets specific immune cells known to drive inflammation in the lungs.
The results are published May 17 in The New England Journal of Medicine.....
Read more here: medicine.wustl.edu
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Blockbuster cancer drug shows surprising promise in treating severe asthma
A blockbuster cancer drug may have a surprising new use: It’s showing real promise in treating severe asthma. That may help researchers better understand the basic biology of the chronic condition — and develop new medications, according to a small proof-of-principle study published on Wednesday in the New England Journal of Medicine.
The trial studied imatinib, known commonly under the brand name Gleevec, in 62 patients with severe and difficult-to-treat asthma. Imatinib is a chemotherapy used to treat leukemia and other cancers.....
Read more here: statnews.com
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Proof-of principle study finds imatinib improves symptoms for patients with severe asthma
In a new, proof-of-principle study researchers have found that targeting the mast cells with imatinib, a drug used to effectively treat certain forms of cancer, improved airway hyperresponsiveness, a measure of the sensitivity of the airway, and decreased the number of mast cells present in the airway. Treatment also produced a small improvement in airway function.....
Read more here: sciencedaily.com
Therapy targets immune cells driving lung inflammation
A small clinical trial suggests that some patients with severe asthma may benefit from treatment with a targeted cancer drug. The study, conducted in part at Washington University School of Medicine in St. Louis, showed that imatinib (brand name Gleevec), commonly prescribed to treat chronic myeloid leukemia, also targets specific immune cells known to drive inflammation in the lungs.
The results are published May 17 in The New England Journal of Medicine.....
Read more here: medicine.wustl.edu
------------------------------------------------------
Blockbuster cancer drug shows surprising promise in treating severe asthma
A blockbuster cancer drug may have a surprising new use: It’s showing real promise in treating severe asthma. That may help researchers better understand the basic biology of the chronic condition — and develop new medications, according to a small proof-of-principle study published on Wednesday in the New England Journal of Medicine.
The trial studied imatinib, known commonly under the brand name Gleevec, in 62 patients with severe and difficult-to-treat asthma. Imatinib is a chemotherapy used to treat leukemia and other cancers.....
Read more here: statnews.com
------------------------------------------------------
Proof-of principle study finds imatinib improves symptoms for patients with severe asthma
In a new, proof-of-principle study researchers have found that targeting the mast cells with imatinib, a drug used to effectively treat certain forms of cancer, improved airway hyperresponsiveness, a measure of the sensitivity of the airway, and decreased the number of mast cells present in the airway. Treatment also produced a small improvement in airway function.....
Read more here: sciencedaily.com
Thursday, May 18, 2017
Asthma problems increase around the first coast
JACKSONVILLE, Fla. - Enjoying the beautiful weekend weather came at a cost for some people who were struggling with what's going around.
The smoke from the wildfires remained an issue this week, according to several doctors. Surprisingly, a couple cases of the flu were reported as well.
According to the CareSpot in Mandarin, a handful of patients tested positive for the flu. A couple other patients had a stomach bug that kept them stuck inside for at least 24-48 hours.....
Read more here: news4jax.com
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Living with asthma: A family's story
A local family shares how they stay active
BAKERSFIELD, Calif. - David Wells has had asthma for most of his life. He grew up in Bakersfield and was diagnosed as a young child. Growing up, he struggled with balancing breathing issues with activities and school. He says his teachers viewed his condition as insignificant because it wasn't contagious. He missed between 25 and 30 days of school a year when he wasn't able to contain his breathing.....
Read more here: turnto23.com
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What's Going Around: Asthma symptoms worse for kids
GRAND FORKS, ND (WDAZ-TV) - In this week's "What's Going Around” - if you're hoarse, you're not alone. Plus, physicians say parents of kids with asthma should make an action plan now.
Dr. Colleen Swank with Altru says in Grand Forks and Crookston, tree pollen and spring allergens are making asthma symptoms worse for kids. Children with asthma should have a written asthma action plan provided by their primary care provider. Those who don't should follow up with their provider to develop one.....
Read more here: wdaz.com
JACKSONVILLE, Fla. - Enjoying the beautiful weekend weather came at a cost for some people who were struggling with what's going around.
The smoke from the wildfires remained an issue this week, according to several doctors. Surprisingly, a couple cases of the flu were reported as well.
According to the CareSpot in Mandarin, a handful of patients tested positive for the flu. A couple other patients had a stomach bug that kept them stuck inside for at least 24-48 hours.....
Read more here: news4jax.com
------------------------------------------------------
Living with asthma: A family's story
A local family shares how they stay active
BAKERSFIELD, Calif. - David Wells has had asthma for most of his life. He grew up in Bakersfield and was diagnosed as a young child. Growing up, he struggled with balancing breathing issues with activities and school. He says his teachers viewed his condition as insignificant because it wasn't contagious. He missed between 25 and 30 days of school a year when he wasn't able to contain his breathing.....
Read more here: turnto23.com
------------------------------------------------------
What's Going Around: Asthma symptoms worse for kids
GRAND FORKS, ND (WDAZ-TV) - In this week's "What's Going Around” - if you're hoarse, you're not alone. Plus, physicians say parents of kids with asthma should make an action plan now.
Dr. Colleen Swank with Altru says in Grand Forks and Crookston, tree pollen and spring allergens are making asthma symptoms worse for kids. Children with asthma should have a written asthma action plan provided by their primary care provider. Those who don't should follow up with their provider to develop one.....
Read more here: wdaz.com
Wednesday, May 17, 2017
Take asthma seriously
Whether asthma symptoms are mild, moderate or severe, they need to be taken seriously.
In fact, Dr. Vincent Hutchinson, a Barbadian Paediatrician, Immunologist and Allergist, is calling on parents to learn more about this chronic disease of the lungs.
“I think that parents need to know exactly what is asthma. They need to know that once you have the diagnosis, you have to try to control it and use the medications that are shown to be effective and safe,” he stressed.....
Read more here: barbadosadvocate.com
------------------------------------------------------
Partners for a Healthier Community Wins Grant for Asthma Project
SPRINGFIELD — The Green & Healthy Homes Initiative (GHHI), following a national competition, has awarded grants and support to Partners for a Healthier Community in Springfield, as well as Community Foundation for Greater Buffalo (Buffalo, N.Y.), Health Net of West Michigan (Grand Rapids, Mich.), and Le Bonheur Community Health and Well-Being (Memphis, Tenn.), to advance their Pay for Success (PFS) projects.....
Read more here: businesswest.com
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Ranked: Where asthma hits hardest in the Seattle-area
King County communities ranked from best to worst by asthma prevalence
It turns out the rich really do breathe easier.
About one in 10 King County residents has asthma, but the affliction isn’t spread evenly. Check out the slideshow above for a look at how Seattle-area communities compare.
Women are significantly more likely than men to have asthma. There appear to be significant racial differences in asthma prevalence -- about 4 percent of residents who described themselves as Asian had asthma, compared to about 10 percent of black or white residents and 7 percent of Hispanic residents.....
Read more here: seattlepi.com
Whether asthma symptoms are mild, moderate or severe, they need to be taken seriously.
In fact, Dr. Vincent Hutchinson, a Barbadian Paediatrician, Immunologist and Allergist, is calling on parents to learn more about this chronic disease of the lungs.
“I think that parents need to know exactly what is asthma. They need to know that once you have the diagnosis, you have to try to control it and use the medications that are shown to be effective and safe,” he stressed.....
Read more here: barbadosadvocate.com
------------------------------------------------------
Partners for a Healthier Community Wins Grant for Asthma Project
SPRINGFIELD — The Green & Healthy Homes Initiative (GHHI), following a national competition, has awarded grants and support to Partners for a Healthier Community in Springfield, as well as Community Foundation for Greater Buffalo (Buffalo, N.Y.), Health Net of West Michigan (Grand Rapids, Mich.), and Le Bonheur Community Health and Well-Being (Memphis, Tenn.), to advance their Pay for Success (PFS) projects.....
Read more here: businesswest.com
------------------------------------------------------
Ranked: Where asthma hits hardest in the Seattle-area
King County communities ranked from best to worst by asthma prevalence
It turns out the rich really do breathe easier.
About one in 10 King County residents has asthma, but the affliction isn’t spread evenly. Check out the slideshow above for a look at how Seattle-area communities compare.
Women are significantly more likely than men to have asthma. There appear to be significant racial differences in asthma prevalence -- about 4 percent of residents who described themselves as Asian had asthma, compared to about 10 percent of black or white residents and 7 percent of Hispanic residents.....
Read more here: seattlepi.com
Tuesday, May 16, 2017
An environmental allergist who was among the first to discover and name the ‘thunderstorm asthma’ phenomenon has warned of the effort needed to avoid another tragedy
Almost six months on from the devastating thunderstorm asthma event that resulted in the deaths of nine Melbourne people, Associate Professor Cenk Suphioglu, from Deakin’s School of Life and Environmental Sciences, said the phenomenon should have been taken more seriously.
“The risk is there every grass pollen season, as long as the two key triggers of thunderstorm asthma are there,” A/Prof Suphioglu said.
“That’s high grass pollen counts, due to a wet winter and spring promoting grass growth and subsequent pollen release.....
Read more here: ajp.com.au
------------------------------------------------------
Parent of asthma sufferer welcomes recommendation
New Zealanders have become "cavalier" when it comes to asthma, as so many people have it that it tends to get minimised, says one researcher.
Associate Professor Jim Reid from Otago University, a respiratory medicine researcher, was responding to a report that revealed the country's high rates of asthma and possible remedies.
One area with a high incidence was the Hutt DHB area, where 17 per cent of children have asthma, some three per cent higher than the national average.....
Read more here: stuff.co.nz
------------------------------------------------------
May Is National Asthma and Allergy Awareness Month
WASHINGTON, May 15, 2017 (GLOBE NEWSWIRE) -- Asthma is a chronic medical condition that affects over 20 million Americans, including 6 million children. It is a lung disorder in which the bronchioles, the inner lining of the small breathing tubes of the lungs, become inflamed and swollen. The muscles in the walls of the bronchioles may spasm, or narrow, causing symptoms of asthma which include chest tightness, wheezing, shortness of breath, or coughing. Individuals with mild asthma may not even be aware they have it, as wheezing may only be audible with a stethoscope if present at all.....
Read more here: globenewswire.com
Almost six months on from the devastating thunderstorm asthma event that resulted in the deaths of nine Melbourne people, Associate Professor Cenk Suphioglu, from Deakin’s School of Life and Environmental Sciences, said the phenomenon should have been taken more seriously.
“The risk is there every grass pollen season, as long as the two key triggers of thunderstorm asthma are there,” A/Prof Suphioglu said.
“That’s high grass pollen counts, due to a wet winter and spring promoting grass growth and subsequent pollen release.....
Read more here: ajp.com.au
------------------------------------------------------
Parent of asthma sufferer welcomes recommendation
New Zealanders have become "cavalier" when it comes to asthma, as so many people have it that it tends to get minimised, says one researcher.
Associate Professor Jim Reid from Otago University, a respiratory medicine researcher, was responding to a report that revealed the country's high rates of asthma and possible remedies.
One area with a high incidence was the Hutt DHB area, where 17 per cent of children have asthma, some three per cent higher than the national average.....
Read more here: stuff.co.nz
------------------------------------------------------
May Is National Asthma and Allergy Awareness Month
WASHINGTON, May 15, 2017 (GLOBE NEWSWIRE) -- Asthma is a chronic medical condition that affects over 20 million Americans, including 6 million children. It is a lung disorder in which the bronchioles, the inner lining of the small breathing tubes of the lungs, become inflamed and swollen. The muscles in the walls of the bronchioles may spasm, or narrow, causing symptoms of asthma which include chest tightness, wheezing, shortness of breath, or coughing. Individuals with mild asthma may not even be aware they have it, as wheezing may only be audible with a stethoscope if present at all.....
Read more here: globenewswire.com
Monday, May 15, 2017
Asthma deaths hit 12-year high in Northern Ireland - teachers plea for support
As Northern Ireland’s asthma deaths hit a 12-year high, teachers say they need more support to help children cope with the life-threatening condition.
“Last week's inquest into the death of a pupil following an allergic reaction highlighted this issue again. The approaching hay fever season, and the asthma attacks it leads to, signals dread for not just sufferers,” according to Avril Hall Callaghan, General Secretary of the Ulster Teachers’ Union.
“The fact that the number of Northern Ireland people who died from asthma last year hit an all-time high highlights the very real dangers of this condition".....
Read more here: belfasttelegraph.co.uk
------------------------------------------------------
Asthma is manageable
Doctors underline the need to inform people about the dos and don’ts of asthma, an ailment which is on the rise in Pakistan.
When people have difficulty in breathing they resort to self-medication or heed to whoever has whatever to suggest. This attitude should be completely shunned. These views were expressed by most pulmonologists at a seminar, titled ‘You Can Control Asthma,’ which was held recently in connection with the World Asthma Day that falls on May 2.....
Read more here: tns.thenews.com.pk
------------------------------------------------------
McLeod children’s hospital hosts asthma camp
FLORENCE, SC (WBTW) – Saturday at McLeod children’s hospital ,a free asthma camp for children who suffer from asthma was hosted.
During the camp, children got the chance to learn how to manage their asthma through fun games.
Game stations demonstrated lung anatomy, as well as asthma medication and proper usage. They were also taught the importance of asthma control during activities such as sports.....
Read more here: wbtw.com
As Northern Ireland’s asthma deaths hit a 12-year high, teachers say they need more support to help children cope with the life-threatening condition.
“Last week's inquest into the death of a pupil following an allergic reaction highlighted this issue again. The approaching hay fever season, and the asthma attacks it leads to, signals dread for not just sufferers,” according to Avril Hall Callaghan, General Secretary of the Ulster Teachers’ Union.
“The fact that the number of Northern Ireland people who died from asthma last year hit an all-time high highlights the very real dangers of this condition".....
Read more here: belfasttelegraph.co.uk
------------------------------------------------------
Asthma is manageable
Doctors underline the need to inform people about the dos and don’ts of asthma, an ailment which is on the rise in Pakistan.
When people have difficulty in breathing they resort to self-medication or heed to whoever has whatever to suggest. This attitude should be completely shunned. These views were expressed by most pulmonologists at a seminar, titled ‘You Can Control Asthma,’ which was held recently in connection with the World Asthma Day that falls on May 2.....
Read more here: tns.thenews.com.pk
------------------------------------------------------
McLeod children’s hospital hosts asthma camp
FLORENCE, SC (WBTW) – Saturday at McLeod children’s hospital ,a free asthma camp for children who suffer from asthma was hosted.
During the camp, children got the chance to learn how to manage their asthma through fun games.
Game stations demonstrated lung anatomy, as well as asthma medication and proper usage. They were also taught the importance of asthma control during activities such as sports.....
Read more here: wbtw.com
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